Take part in a Hallam PhD research study investigating the effect of low-levels of carbon monoxide on the human brain.

What is the purpose of the research?

Most individuals are exposed to carbon monoxide every day, often through car pollution and smoking. Prolonged exposure can have long-term effects on the body, but we don't yet understand if these effects can be reduced or reversed with different actions. The research will use magnetic resonance imaging (MRI scans) and transcranial doppler ultrasounds (TCDs) to look at the way the brain works, in particular how very low levels of carbon monoxide, like what you are exposed to typically, may affect MRI and TCD scan results.

Who should take part?

To take part you must be between the ages of 18 and 55, healthy, and have either never smoked or have smoked at least 10 cigarettes a day for at least 3 years. If female, participants should currently be on a method of hormonal contraception, such as the oral contraceptive pill.

If you have any questions about suitability for the study, feel free to email lucie.wilson@shu.ac.uk.

How do I take part?

If you're interested in taking part, please read either the non-smoker or smoker participant information sheet.

If you're happy to enrol, please email lucie.wilson@shu.ac.uk and you'll be sent a consent form and health questionnaire. Scans can then be completed at a day/time that suits you.

How can I find out about the results of the study?

Results will be published in a scientific journal, and they will also form the basis of a PhD student's thesis, however scan data will be anonymous. After the study you may ask any questions of the researchers present and they will provide you with a written copy of the study's findings, should you wish to receive them.

Deadline

Scan dates are available now and enrolment will be open for the next 6 months.

If you have any questions about the research or giving your consent, please contact:

Lucie Wilson (Researcher)

lucie.wilson@shu.ac.uk